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1

β-Mannosynthase: Synthesis of β-Mannosides with a Mutant β-Mannosidase

Oyekanmi Nashiru, David L. Zechel, Dominik Stoll, Taraneh Mohammadzadeh, R. Antony J. Warren, Stephen G. Withers

Journal:

Angewandte Chemie

Year:

2001

Language:

english

File:

PDF, 175 KB

english, 2001

2

Changing Biosynthetic Profiles by Expressing bldA in Streptomyces Strains

Gessner, Arne, Heitzler, Tanja, Zhang, Songya, Klaus, Christine, Murillo, Renato, Zhao, Hanna, Vanner, Stephanie, Zechel, David L., Bechthold, Andreas

Journal:

Year:

2015

Language:

english

File:

PDF, 882 KB

english, 2015

3

Corrigendum: Changing Biosynthetic Profiles by Expressing bldA in Streptomyces Strains

Gessner, Arne, Heitzler, Tanja, Zhang, Songya, Klaus, Christine, Murillo, Renato, Zhao, Hanna, Vanner, Stephanie, Zechel, David L., Bechthold, Andreas

Journal:

Year:

2016

File:

PDF, 163 KB

2016

4

Secondary nucleotide messenger c-di-GMP exerts a global control on natural product biosynthesis in streptomycetes

Makitrynskyy, Roman, Tsypik, Olga, Nuzzo, DesirÃ¨e, Paululat, Thomas, Zechel, David L, Bechthold, Andreas

Journal:

Nucleic Acids Research

Year:

2020

File:

PDF, 3.42 MB

2020

5

Substrate Distortion by a β-Mannanase: Snapshots of the Michaelis and Covalent-Intermediate Complexes Suggest a B2,5 Conformation for the Transition State

Valérie M.-A. Ducros, David L. Zechel, Garib N. Murshudov, Harry J. Gilbert, Lóránd Szabó, Dominik Stoll, Stephen G. Withers, Gideon J. Davies

Journal:

Angewandte Chemie

Year:

2002

Language:

english

File:

PDF, 135 KB

english, 2002

6

β-Mannosynthase: Synthesis of β-Mannosides with a Mutant β-Mannosidase

Oyekanmi Nashiru, David L. Zechel, Dominik Stoll, Taraneh Mohammadzadeh, R. Antony J. Warren, Stephen G. Withers

Journal:

Angewandte Chemie International Edition

Year:

2001

Language:

english

File:

PDF, 176 KB

english, 2001

7

Substrate Distortion by a β-Mannanase: Snapshots of the Michaelis and Covalent-Intermediate Complexes Suggest a B2,5 Conformation for the Transition State

Valérie M.-A. Ducros, David L. Zechel, Garib N. Murshudov, Harry J. Gilbert, Lóránd Szabó, Dominik Stoll, Stephen G. Withers, Gideon J. Davies

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 134 KB

english, 2002

8

Neuronal migration is transiently delayed by prenatal exposure to intermittent hypoxia

Jennifer L. Zechel, Jorge L. Gamboa, Allyn G. Peterson, Michelle A. Puchowicz, Warren R. Selman, W. David Lust

Journal:

Birth Defects Research Part B: Developmental and Reproductive Toxicology

Year:

2005

Language:

english

File:

PDF, 882 KB

english, 2005

9

Combinatorial Approaches To Novel Proteins

Tomoaki Matsuura, Andreas Ernst, David L. Zechel, Andreas Plückthun

Journal:

Year:

2004

Language:

english

File:

PDF, 129 KB

english, 2004

10

Rebeccamycin and Staurosporine Biosynthesis: Insight into the Mechanisms of the Flavin-Dependent Monooxygenases RebC and StaC

Katherine Groom, Dr. Anupam Bhattacharya , Prof. David L. Zechel

Journal:

Year:

2011

Language:

english

File:

PDF, 273 KB

english, 2011

11

ChemInform Abstract: Glycosidase Mechanisms: Anatomy of a Finely Tuned Catalyst

David L. Zechel, Stephen G. Withers

Journal:

Year:

2000

File:

PDF, 24 KB

2000

12

ChemInform Abstract: β-Mannosynthase: Synthesis of β-Mannosides with a Mutant β-Mannosidase.

Oyekanmi Nashiru, David L. Zechel, Dominik Stoll, Taraneh Mohammadzadeh, R. Antony J. Warren, Stephen G. Withers

Journal:

Year:

2001

File:

PDF, 26 KB

2001

13

Combinatorial Approaches to Novel Proteins

Tomoaki Matsuura, Andreas Ernst, David L. Zechel, Andreas Plueckthun

Journal:

Year:

2004

File:

PDF, 48 KB

2004

14

Alterations in matrix metalloproteinase-9 levels and tissue inhibitor of matrix metalloproteinases-1 expression in a transforming growth factor-β transgenic model of hydrocephalus

Jennifer Zechel, Harsh Gohil, W. David Lust, Alan Cohen

Journal:

Journal of Neuroscience Research

Year:

2002

Language:

english

File:

PDF, 1.90 MB

english, 2002

15

A fluorescent substrate for carbon–phosphorus lyase: Towards the pathway for organophosphonate metabolism in bacteria

Shu-Mei He, Yan Luo, Bjarne Hove-Jensen, David L. Zechel

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 395 KB

english, 2009

16

Rational Design of an Aryl-C-Glycoside Catalyst from a Natural Product O-Glycosyltransferase

Johannes Härle, Stefan Günther, Benjamin Lauinger, Monika Weber, Bernd Kammerer, David L. Zechel, Andriy Luzhetskyy, Andreas Bechthold

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.16 MB

english, 2011

17

Characterization of covalently bonded proteins on poly(methyl methacrylate) by X-ray photoelectron spectroscopy

Geoffrey W. Nelson, Megan Perry, Shu-Mei He, David L. Zechel, J. Hugh Horton

Journal:

Colloids and Surfaces B: Biointerfaces

Year:

2010

Language:

english

File:

PDF, 988 KB

english, 2010

18

Anatomy of Glycosynthesis: Structure and Kinetics of the Humicola insolens Cel7B E197A and E197S Glycosynthase Mutants

Valérie M-A Ducros, Chris A Tarling, David L Zechel, A.Marek Brzozowski, Torben P Frandsen, Ingemar von Ossowski, Martin Schülein, Stephen G Withers, Gideon J Davies

Journal:

Chemistry & Biology

Year:

2003

Language:

english

File:

PDF, 271 KB

english, 2003

19

Dissection of nucleophilic and acid–base catalysis in glycosidases

David L Zechel, Stephen G Withers

Journal:

Current Opinion in Chemical Biology

Year:

2001

Language:

english

File:

PDF, 170 KB

english, 2001

20

Regional metabolic status of the E–18 rat fetal brain following transient hypoxia/ischemia

Svetlana Pundik, Shenandoah Robinson, W. David Lust, Jennifer Zechel, Marek Buczek, Warren R. Selman

Journal:

Metabolic Brain Disease

Year:

2006

Language:

english

File:

PDF, 294 KB

english, 2006

21

Neuroprotection in diet-induced ketotic rat brain after focal ischemia

Puchowicz, Michelle A, Zechel, Jennifer L, Valerio, Jose, Emancipator, Douglas S, Xu, Kui, Pundik, Svetlana, LaManna, Joseph C, Lust, W David

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2008

Language:

english

File:

PDF, 300 KB

english, 2008

22

Caspase-9 Inhibition after Focal Cerebral Ischemia Improves Outcome following Reversible Focal Ischemia

Graham Mouw, Jennifer L. Zechel, Yifang Zhou, W. David Lust, Warren R. Selman, Robert A. Ratcheson

Journal:

Metabolic Brain Disease

Year:

2002

Language:

english

File:

PDF, 350 KB

english, 2002

23

PhnY and PhnZ Comprise a New Oxidative Pathway for Enzymatic Cleavage of a Carbon–Phosphorus Bond

McSorley, Fern R., Wyatt, Peter B., Martinez, Asuncion, DeLong, Edward F., Hove-Jensen, Bjarne, Zechel, David L.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 554 KB

english, 2012

24

Novel Treatment of Atypical Human Papillomavirus-Associated Epithelial Hyperplasia With Cidofovir

David C. Collette, Marc A. Zechel

Journal:

Journal of Oral and Maxillofacial Surgery

Year:

2011

Language:

english

File:

PDF, 535 KB

english, 2011

25

Chloramphenicol Biosynthesis: The Structure of CmlS, a Flavin-Dependent Halogenase Showing a Covalent Flavin–Aspartate Bond

Kateryna Podzelinska, Ryan Latimer, Anupam Bhattacharya, Leo C. Vining, David L. Zechel, Zongchao Jia

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 2.80 MB

english, 2010

26

The E358S mutant of Agrobacterium sp. β-glucosidase is a greatly improved glycosynthase

Christoph Mayer, David L. Zechel, Stephen P. Reid, R.Antony J. Warren, Stephen G. Withers

Journal:

Year:

2000

Language:

english

File:

PDF, 129 KB

english, 2000

27

Understanding How Diverse β-Mannanases Recognize Heterogeneous Substrates

Tailford, Louise E., Ducros, Valerie M.-A., Flint, James E., Roberts, Shirley M., Morland, Carl, Zechel, David L., Smith, Nicola, Bjo̷rnvad, Mads E., Borchert, Torben V., Wilson, Keith S., Davies, Gid

Journal:

Year:

2009

Language:

english

File:

PDF, 2.97 MB

english, 2009

28

Iminosugar Glycosidase Inhibitors: Structural and Thermodynamic Dissection of the Binding of Isofagomine and 1-Deoxynojirimycin to β-Glucosidases

Zechel, David L., Boraston, Alisdair B., Gloster, Tracey, Boraston, Catherine M., Macdonald, James M., Tilbrook, D. Matthew G., Stick, Robert V., Davies, Gideon J.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 478 KB

english, 2003

29

A concise synthesis of α- D -ribofuranosyl alkylphosphonates Putative substrate intermediates for the carbonphosphorous lyase system

Luo, Yan, Zechel, David L

Journal:

Canadian Journal of Chemistry

Year:

2006

Language:

english

File:

PDF, 87 KB

english, 2006

30

Structure of the Michaelis complex of β-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis

Offen, Wendy A., Zechel, David L., Withers, Stephen G., Gilbert, Harry J., Davies, Gideon J.

Journal:

Chemical Communications

Year:

2009

Language:

english

File:

PDF, 618 KB

english, 2009

31

A Cryptic Polyene Biosynthetic Gene Cluster in Streptomyces calvus Is Expressed upon Complementation with a Functional bldA Gene

Kalan, Lindsay, Gessner, Arne, Thaker, Maulik N., Waglechner, Nicholas, Zhu, XiMing, Szawiola, Anjuli, Bechthold, Andreas, Wright, Gerard D., Zechel, David L.

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 1.78 MB

english, 2013

32

METHOD OF PREPARING HISTOLOGICAL SPECIMENS OF THE COCHLEA.

Kalan, Lindsay, Gessner, Arne, Thaker, Maulik N., Waglechner, Nicholas, Zhu, XiMing, Szawiola, Anjuli, Bechthold, Andreas, Wright, Gerard D., Zechel, David L.

Journal:

Year:

1893

Language:

english

File:

PDF, 183 KB

english, 1893

33

Thermal and Transition-Metal-Catalyzed Ring-Opening Polymerization (ROP) of [1]Silaferrocenophanes with Chlorine Substituents at Silicon: A Route to Tunable Poly(ferrocenylsilanes)

Zechel, David L., Hultzsch, Kai C., Rulkens, Ron, Balaishis, David, Ni, Yizeng, Pudelski, John K., Lough, Alan J., Manners, Ian, Foucher, Daniel A.

Journal:

Organometallics

Year:

1996

Language:

english

File:

PDF, 258 KB

english, 1996

34

Mechanism, Mutagenesis, and Chemical Rescue of a β-Mannosidase from Cellulomonas fimi †

Zechel, David L., Reid, Stephen P., Stoll, Dominik, Nashiru, Oyekanmi, Warren, R. Antony J., Withers, Stephen G.

Journal:

Year:

2003

Language:

english

File:

PDF, 148 KB

english, 2003

35

Physiological Role of phnP -specified Phosphoribosyl Cyclic Phosphodiesterase in Catabolism of Organophosphonic Acids by the Carbon−Phosphorus Lyase Pathway

Hove-Jensen, Bjarne, McSorley, Fern R., Zechel, David L.

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

36

Structure and Mechanism of PhnP, a Phosphodiesterase of the Carbon-Phosphorus Lyase Pathway

He, Shu-Mei, Wathier, Matthew, Podzelinska, Kateryna, Wong, Matthew, McSorley, Fern R., Asfaw, Alemayehu, Hove-Jensen, Bjarne, Jia, Zongchao, Zechel, David L.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.55 MB

english, 2011

37

Enzymatic Synthesis of Carbon−Fluorine Bonds

Zechel, David L., Reid, Stephen P., Nashiru, Oyekanmi, Mayer, Christoph, Stoll, Dominik, Jakeman, David L., Warren, R. Antony J., Withers, Stephen G.

Journal:

Journal of the American Chemical Society

Year:

2001

Language:

english

File:

PDF, 34 KB

english, 2001

38

Pre-Steady State Kinetic Analysis of an Enzymatic Reaction Monitored by Time-Resolved Electrospray Ionization Mass Spectrometry †

Zechel, David L., Konermann, Lars, Withers, Stephen G., Douglas, D. J.

Journal:

Year:

1998

Language:

english

File:

PDF, 133 KB

english, 1998

39

Glycosidase Inhibition: An Assessment of the Binding of 18 Putative Transition-State Mimics

Gloster, Tracey M., Meloncelli, Peter, Stick, Robert V., Zechel, David, Vasella, Andrea, Davies, Gideon J.

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 608 KB

english, 2007

40

Direct Observation of the Protonation State of an Imino Sugar Glycosidase Inhibitor upon Binding

Varrot, Annabelle, Tarling, Chris A., Macdonald, James M., Stick, Robert V., Zechel, David L., Withers, Stephen G., Davies, Gideon J.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 69 KB

english, 2003

41

Fluorescence resonance energy transfer analysis of the structure of the four-way DNA junction

Clegg, Robert M., Murchie, Alastair I. H., Zechel, Annelies, Carlberg, Carsten, Diekmann, Stephan, Lilley, David M. J.

Journal:

Year:

1992

Language:

english

File:

PDF, 2.46 MB

english, 1992

42

Synthesis, structural characterization, electrochemical properties and polymerization behaviour of the first silicon-bridged [1.1]ferrocenophane [{Fe(?-C5H4)2SiMe2}2]

Zechel, David L., Foucher, Daniel A., Pudelski, John K., Yap, Glenn P. A., Rheingold, Arnold L., Manners, Ian

Journal:

Journal of the Chemical Society Dalton Transactions

Year:

1995

Language:

english

File:

PDF, 906 KB

english, 1995

43

[ACM Press the 10th annual conference - Atlanta, GA, USA (2008.07.12-2008.07.16)] Proceedings of the 10th annual conference on Genetic and evolutionary computation - GECCO '08 - A multi-objective ant colony approach for pareto-optimization using dynamic programming

Häckel, Sascha, Fischer, Marco, Zechel, David, Teich, Tobias

Year:

2008

Language:

english

File:

PDF, 731 KB

english, 2008

44

An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products

Johnston, Chad W., Skinnider, Michael A., Wyatt, Morgan A., Li, Xiang, Ranieri, Michael R. M., Yang, Lian, Zechel, David L., Ma, Bin, Magarvey, Nathan A.

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 931 KB

english, 2015

45

Antitumor compounds fromStreptomycessp. KML-2, isolated from Khewra salt mines, Pakistan

Aftab, Usman, Zechel, David L., Sajid, Imran

Journal:

Biological Research

Year:

2015

Language:

english

File:

PDF, 1.86 MB

english, 2015

46

Five phosphonate operon gene products as components of a multi-subunit complex of the carbon-phosphorus lyase pathway

Bjarne Jochimsen, Signe Lolle, Fern R. McSorley, Mariah Nabi, Jens Stougaard, David L. Zechel and Bjarne Hove-Jensen

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.06 MB

english, 2011

47

Characterization of a model of hydrocephalus in transgenic mice

Cohen, Alan R., Leifer, David W., Zechel, Marc, Flaningan, Daniel P., Lewin, Jonathan S., Lust, W. David

Journal:

Journal of Neurosurgery

Year:

1999

Language:

english

File:

PDF, 932 KB

english, 1999

48

Observing the Helical Geometry of Double-Stranded DNA in Solution by Fluorescence Resonance Energy Transfer

Robert M. Clegg, Alastair I. H. Murchie, Annelies Zechel and David M. J. Lilley

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.08 MB

english, 1993

49

PhnK: Another Piece of the Carbon-Phosphorus Lyase Puzzle

Zechel, David L.

Journal:

Year:

2016

Language:

english

File:

PDF, 421 KB

english, 2016

50

Activation of caspase-12, an endoplasmic reticulum resident caspase, after permanent focal ischemia in rat

Mouw, Graham, Zechel, Jennifer L., Gamboa, Jorge, Lust, W. David, Selman, Warren R., Ratcheson, Robert A.

Journal:

Year:

2003

Language:

english

File:

PDF, 147 KB

english, 2003

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